{"id":1591,"date":"2013-06-01T07:16:27","date_gmt":"2013-06-01T07:16:27","guid":{"rendered":"https:\/\/mycor.iam.inrae.fr\/IAM\/?p=1591"},"modified":"2013-06-10T20:47:32","modified_gmt":"2013-06-10T20:47:32","slug":"article-febs-letters","status":"publish","type":"post","link":"https:\/\/mycor.iam.inrae.fr\/IAM\/?p=1591","title":{"rendered":"Article: FEBS Letters"},"content":{"rendered":"<p><a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0014579313003852\">Atypical features of a Ure2p glutathione transferase from <em>Phanerochaete chrysosporium<\/em><\/a><\/p>\n<div>\n<div>Anne Thuillier, Thomas Roret, Fr\u00e9d\u00e9rique Favier, Eric Gelhaye, Jean-Pierre Jacquot, Claude Didierjean, M\u00e9lanie Morel-Rouhier<\/div>\n<\/div>\n<h2><\/h2>\n<h2 id=\"section_abstract\">Abstract<\/h2>\n<p id=\"sp0010\" style=\"text-align: justify;\">Glutathione transferases (GSTs) are known to transfer glutathione onto small hydrophobic molecules in detoxification reactions. The GST Ure2pB1 from\u00a0<em>Phanerochaete chrysosporium<\/em>\u00a0exhibits atypical features, i.e. the presence of two glutathione binding sites and a high affinity towards oxidized glutathione. Moreover, PcUre2pB1 is able to efficiently deglutathionylate GS-phenacylacetophenone. Catalysis is not mediated by the cysteines of the protein but rather by the one of glutathione and an asparagine residue plays a key role in glutathione stabilization. Interestingly PcUre2pB1 interacts in vitro with a GST of the omega class. These properties are discussed in the physiological context of wood degrading fungi.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Atypical features of a Ure2p glutathione transferase from Phanerochaete chrysosporium Anne Thuillier, Thomas Roret, Fr\u00e9d\u00e9rique Favier, Eric Gelhaye, Jean-Pierre Jacquot, Claude Didierjean, M\u00e9lanie Morel-Rouhier Abstract Glutathione transferases (GSTs) are known to transfer glutathione onto small hydrophobic molecules in detoxification reactions. &hellip; <a href=\"https:\/\/mycor.iam.inrae.fr\/IAM\/?p=1591\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[],"class_list":["post-1591","post","type-post","status-publish","format-standard","hentry","category-academic-productions"],"_links":{"self":[{"href":"https:\/\/mycor.iam.inrae.fr\/IAM\/index.php?rest_route=\/wp\/v2\/posts\/1591","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mycor.iam.inrae.fr\/IAM\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mycor.iam.inrae.fr\/IAM\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mycor.iam.inrae.fr\/IAM\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/mycor.iam.inrae.fr\/IAM\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1591"}],"version-history":[{"count":0,"href":"https:\/\/mycor.iam.inrae.fr\/IAM\/index.php?rest_route=\/wp\/v2\/posts\/1591\/revisions"}],"wp:attachment":[{"href":"https:\/\/mycor.iam.inrae.fr\/IAM\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1591"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mycor.iam.inrae.fr\/IAM\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1591"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mycor.iam.inrae.fr\/IAM\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1591"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}