Post-doctoral position on poplar rust fungus effectors at INRA Nancy (France)
A one-year post-doc position is available in the EcoGenomic of Interactions team at INRA Nancy starting in november 2013 on the functional analysis of the poplar-poplar rust fungus pathosystem. This position is supported POPRUST and the INTEGRARUST projects (french ANR & Labex ARBRE).
Context: Through genomics and transcriptomics, our team has selected a list of promising candidate effectors from the rust fungus pathogen Melampsora larici-populina that we would like to further study to understand their role during host infection. The present project is a follow-up of a former post-doc, thus candidate effectors selection has already been established in the lab.
Duties: In the present project, the successful applicant will focus on the most promising effectors towards their production (recombinant proteins in E. coli, structure and localization, with engaged collaborations for NMR & crystallography) and the search for plant partners both in poplar host plants and heterologous systems.
Duration: 12 months, starting in November 2013
Place of work: The EGI Lab is part of the Tree-Microbe Interactions Department (https://mycor.iam.inrae.fr/IAM/) offers a creative and stimulating international environment and is one of six departments making up the cluster of Laboratoires d’Excellence (LabEx) ARBRE (http://mycor.nancy.inra.fr/ARBRE/). Our lab is located in the Lorraine INRA Center (trees and forest ecosystems research center) which is in the middle of the Champenoux forest just 20 kilometers from the city of Nancy in north-eastern France. The successful applicant will be based at the INRA Center in the EGI Lab but will work in close collaboration with biochemists also part of our department at the Université de Lorraine.
How to apply? Please send your CV and a cover letter describing your research experience and research interests as well as your research goals by email to duplessi@nancy.inra.fr. Include reference(s) from former lab(s) and pdf or links to selected publications.
Contact:
Dr Sébastien Duplessis (INRA scientist)
http://mycor.nancy.inra.fr/GIteam/?page_id=13
e-mail, duplessi@nancy.inra.fr
UMR 1136 Interactions Arbre-Microorganismes
Equipe EcoGénomique des Interactions
Centre INRA Nancy Lorraine
54280 Champenoux
France
Published papers from the team related to the project
• Haquard S, Joly DJ, Lin Y-C, Tisserant E, Feau N, Delaruelle C, Legué V, Kohler A, Tanguay P, Petre B, Frey P, Van De Peer Y, Rouzé P, Martin F, Hamelin RC, Duplessis S (2012) A comprehensive analysis of genes encoding small secreted proteins identifies candidate effectors in Melampsora larici-populina (poplar leaf rust). Molecular Plant-Microbe Interactions, 25:279-293.
• Duplessis S, Cuomo CA, Lin Y-C, Aerts A, Tisserant E, Veneault-Fourrey C, Joly DL, Hacquard S, et al. (2011) Obligate biotrophy features unraveled by the genomic analysis of rust fungi. Proceedings of the National Academy of Science USA, 108:9166-9171. Open Access.
• Duplessis S, Hacquard S, Delaruelle C, Tisserant E, Frey P, Martin F, Kohler A (2011) Melampsora larici-populina transcript profiling during germination and time-course infection of poplar leaves reveals dynamic expression patterns associated with virulence and biotrophy. Molecular Plant-Microbe Interactions, 24:808-818.
• Duplessis S, Joly DJ, Dodds PN (2012) Rust effectors. Chapter 7 In Effectors in Plant-Microbes Interactions, Martin F and Kamoun S (eds), Wiley-Blackwell, pp-155-193.
• Hacquard S, Petre B, Frey P, Hecker A, Rouhier N, Duplessis S (2011) The poplar-poplar rust interaction: insights from genomics and transcriptomics. Journal of Pathogens Vol. 2011, Article ID 716041, 11 pages (doi:10.4061/2011/716041)
