Monthly Archives: June 2013

Séminaire B. Pêtre

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Le séminaire de ce vendredi 14 juin sera animé par Benjamin Pêtre, anciennement doctorant dans notre unité et actuellement en post-doctorat au sein du prestigieux Sainsbury Laboratory dans l’équipe de Sophien Kamoun. Le séminaire sera intitulé: “Rust effectors: where do they go ?”

Friday seminar (14th of june) will be given by Benjamin Pêtre. Benjamin did his PhD in our laboratory and is now doing his post-doc at the Sainsbury Lab in Cambridge, in the team of Pr. Sophien Kamoun. The title of his talk (which will be given in english) is: “Rust effectors: where do they go ?”.

Séminaire: M. Royer (LAE)

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Le séminaire du vendredi (7 juin) sera présenté par Mathilde Royer du Laboratoire Agronomie-Environnement (INRA/Université de Lorraine). Mathilde, qui a récemment soutenu sa thèse, nous présentera ses travaux de doctorat: “Etude des relations entre croissance, concentrations en métabolites primaires et secondaires et disponibilité en ressources chez la tomate avec ou sans bioagresseurs”.
La présentation débutera à 13h30 en salle de réunion du batiment LGEF.

Article: FEBS Letters

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Atypical features of a Ure2p glutathione transferase from Phanerochaete chrysosporium

Anne Thuillier, Thomas Roret, Frédérique Favier, Eric Gelhaye, Jean-Pierre Jacquot, Claude Didierjean, Mélanie Morel-Rouhier

Abstract

Glutathione transferases (GSTs) are known to transfer glutathione onto small hydrophobic molecules in detoxification reactions. The GST Ure2pB1 from Phanerochaete chrysosporium exhibits atypical features, i.e. the presence of two glutathione binding sites and a high affinity towards oxidized glutathione. Moreover, PcUre2pB1 is able to efficiently deglutathionylate GS-phenacylacetophenone. Catalysis is not mediated by the cysteines of the protein but rather by the one of glutathione and an asparagine residue plays a key role in glutathione stabilization. Interestingly PcUre2pB1 interacts in vitro with a GST of the omega class. These properties are discussed in the physiological context of wood degrading fungi.